Symbol
Name
ID

Gabra5
gamma-aminobutyric acid type A receptor subunit alpha 5
MGI:95617

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Secondary microcephaly

Spasticity

CNS hypomyelination

Cerebral cortical atrophy

Hypoplasia of the corpus callosum

Frontotemporal cerebral atrophy

Autism

Intellectual disability, severe

Global developmental delay

Motor delay

Seizure

Bilateral tonic-clonic seizure with generalized onset

Migrating focal seizure

Myoclonic seizure

Tonic seizure

Status epilepticus

Disease(s) Associated with GABRA5

developmental and epileptic encephalopathy 79

Mouse Phenotypes		cochlear inner hair cell degeneration	abnormal cochlear OHC efferent innervation pattern	cochlear outer hair cell degeneration	abnormal hippocampus CA1 region morphology	cochlear ganglion degeneration	abnormal GABA-mediated receptor currents	abnormal inhibitory postsynaptic currents	abnormal long-term potentiation	decreased prepulse inhibition
Availability	Mouse Genotype	cochlear inner hair cell degeneration	abnormal cochlear OHC efferent innervation pattern	cochlear outer hair cell degeneration	abnormal hippocampus CA1 region morphology	cochlear ganglion degeneration	abnormal GABA-mediated receptor currents	abnormal inhibitory postsynaptic currents	abnormal long-term potentiation	decreased prepulse inhibition
	Gabra5^tm1.1Uru/Gabra5^tm1.1Uru
	Gabra5^tm1Twr/Gabra5^tm1Twr

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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